Staphylococcus aureus Fur regulates the expression of virulence factors 1 that contribute to the pathogenesis of pneumonia 2 Running Title : Fur affects exoprotein expression 3
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چکیده
Running Title: Fur affects exoprotein expression 3 Victor J. Torres, Ahmed S. Attia, William J. Mason, M. Indriati Hood, Brian D. 4 Corbin, Federico C. Beasley, Kelsi L. Anderson, Devin L. Stauff, W. Hayes 5 McDonald, Lisa J. Zimmerman, David B. Friedman, David E. Heinrichs, Paul M. 6 Dunman and Eric P. Skaar 7 8 Department of Microbiology and Immunology, Department of Medicine, Mass 9 Spectrometry Research Center, Vanderbilt University Medical Center, 1161 21st Ave. 10 South, Nashville, TN. U.S.A. 37232-2363; Department of Microbiology and Immunology, 11 Infectious Diseases Research Group, Siebens-Drake Medical Research Institute, 12 University of Western Ontario London, Ontario, Canada N6A 5C1; Department of 13 Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE. 14 U.S.A., 68198-5900, Department of Microbiology and Immunology, Faculty of 15 Pharmacy, Cairo University, Cairo 11562, Egypt. 16 Present address: Department of Microbiology, New York University School of Medicine 17 18 *Corresponding Author: Mailing address: Eric P. Skaar, Department of Microbiology and 19 Immunology, Vanderbilt University Medical Center, 1161 21 Avenue South, MCN A20 5102, Nashville, TN 37027. Phone: (615)-343-0002. Fax: (615)-343-7392. E-mail: 21 [email protected] 22 Copyright © 2010, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. Infect. Immun. doi:10.1128/IAI.01423-09 IAI Accepts, published online ahead of print on 25 January 2010
منابع مشابه
Staphylococcus aureus fur regulates the expression of virulence factors that contribute to the pathogenesis of pneumonia.
The tremendous success of Staphylococcus aureus as a pathogen is due to the controlled expression of a diverse array of virulence factors. The effects of host environments on the expression of virulence factors and the mechanisms by which S. aureus adapts to colonize distinct host tissues are largely unknown. Vertebrates have evolved to sequester nutrient iron from invading bacteria, and iron a...
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